Evangelion units are living monsters, cloned from cosmic entities and restrained by armor. Shinji pilots Unit-01, which houses his deceased mother's soul, fusing him neurologically with a monster carrying her ghost.
Van Fanel binds himself to Escaflowne via a blood pact, causing every injury the mech sustains to manifest as a real, unhealing wound on his body until repairs are made.
Activating Valvrave requires Haruto to resign his humanity, granting him immortality, rapid healing, and the ability to transfer consciousness by biting others, a unique vampiric twist.
The Animatrix, an anthology of nine shorts, delves into the Matrix universe. Its most disturbing segments, 'The Second Renaissance Parts 1 and 2,' document the horrifying Machine War.
Humanity's last defense against the insectoid Blue are fragile Armored Shrikes, easily torn apart. Yuji awakens to a world where Earth is overrun, and humans are food for these giant creatures.
Middle schoolers sign a mysterious contract to pilot a giant robot, believing it's a game. They soon discover that each battle victory comes at the cost of the pilot's life.
A millennium after the Gauna destroyed Earth, humanity drifts through space on generation ships. These alien entities have no discernible motives or biology, posing an incomprehensible threat.
Child soldiers, or 'human debris,' undergo dangerous spinal surgery for the Alaya-Vijnana System, linking them directly to mobile suits. This procedure has a high failure rate, often resulting in paralysis or death.
In Arkham City, detective Kurou Daijuuji finds Al Azif, the Necronomicon's manifestation, who contracts with him. This activates Demonbane, a god-like magical construct in a Lovecraftian tale.
Tsutsujidai is a looping city where Kaiju attacks are reset, and victims forgotten. This fabricated digital world is controlled by Akane Shinjo, an isolated teen with god-like creative power.