Nicholas D. Wolfwood's massive, cross-shaped Punisher from Trigun is a heavy firearm designed for superhuman strength, making him a one-man army.
Frieren's elegant, simple staff from Frieren: Beyond Journey's End is the ultimate magical conduit for an elf who has mastered magic over a millennium.
Asta's Demon Dweller Sword from Black Clover is a unique anti-magic blade, perfect for a wielder with no mana to absorb spells and launch powerful counter-attacks.
Forged from a demon's fang, Inuyasha's Tessaiga is a sword of salvation that can seal yokai in eternal slumber, despite its dull appearance.
Ryujin Jakka, Captain-General Yamamoto's Zanpakuto from Bleach, is the oldest and most powerful fire-type blade, capable of burning as hot as the sun's core.